Description

1,2,3-Trifluorobenzene is a high-purity fluorinated aromatic compound, valued for its unique electronic properties and role as a versatile building block in advanced chemical synthesis. Its trifluoromethyl-substituted benzene core makes it an essential intermediate for creating complex molecules with enhanced stability and specific reactivity. This product is primarily sought by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic rings to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms improves efficacy and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce the 1,2,3-trifluorobenzene moiety into more complex structures.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new reaction pathways and developing novel fluorinated compounds.
• Specialty Polymer Modification: Used to incorporate fluorine into polymer backbones, enhancing properties like chemical resistance, thermal stability, and lowering dielectric constants.

Basic Information

Product Name	1,2,3-Trifluorobenzene
CAS No.	1489-53-8
Molecular Formula	C6H3F3
Molecular Weight	132.08 g/mol
Synonyms	1,2,3-Trifluorobenzene; Benzene, 1,2,3-trifluoro-; vic-Trifluorobenzene; 1,2,3-Trifluorobenzol; AS-562/4025000; SCHEMBL194786; 1,2,3-Trifluoro-benzene; Trifluorobenzene (mixed isomers)
EINECS	Contact for details

Quality Control

Our 1,2,3-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.33 g/mL
Boiling Point	~94-96°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.