Description

3,5-Dichlorofluorobenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules in research and industrial applications. This compound is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the dichlorofluoro-benzene moiety imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display and lighting applications.
• Polymer & Resin Modifiers: Incorporated to create specialty polymers with enhanced chemical resistance or specific dielectric properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Building Block: Utilized in nucleophilic aromatic substitution and functional group transformations in complex molecule assembly.

Basic Information

Product Name	3,5-Dichlorofluorobenzene
CAS No.	1435-46-7
Molecular Formula	C6H3Cl2F
Molecular Weight	164.99 g/mol
Synonyms	1,3-Dichloro-5-fluorobenzene; 5-Fluoro-1,3-dichlorobenzene; m-Dichlorofluorobenzene; Fluorobenzene, 3,5-dichloro-; Benzene, 1,3-dichloro-5-fluoro-; 3,5-Dichlorophenyl fluoride
EINECS	215-858-9

Quality Control

Our 3,5-Dichlorofluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, supporting compliance with cGMP and ISO standards for intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.48 g/cm³
Boiling Point	~173-175°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.