Description

1-Bromo-2,3,4,5-tetrafluorobenzene is a versatile fluorinated aromatic building block, valued for its unique combination of halogen and fluorine substituents which impart significant electronic and steric properties. This compound is essential for introducing the tetrafluorophenylene moiety into complex molecular architectures, enabling precise tuning of material characteristics. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in catalysis, ligand synthesis, and the development of liquid crystals and organic semiconductors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic rings that can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved thermal stability and electronic properties.
• Catalyst & Ligand Development: Employed in the preparation of specialized ligands for transition metal catalysis, leveraging the electron-withdrawing effect of the fluorine atoms.
• Polymer & Advanced Material Modifier: Incorporated into high-performance polymers and coatings to impart chemical resistance, low surface energy, and thermal stability.
• Chemical Research & Development: A valuable reagent for exploring new reactions in organic synthesis and material science due to its distinct reactivity pattern.

Basic Information

Product Name	1-Bromo-2,3,4,5-Tetrafluorobenzene
CAS No.	1074-91-5
Molecular Formula	C6HBrF4
Molecular Weight	244.97 g/mol
Synonyms	2,3,4,5-Tetrafluorobromobenzene; Benzene, 1-bromo-2,3,4,5-tetrafluoro-; 1-Bromo-2,3,4,5-tetrafluorobenzol; Bromotetrafluorobenzene; NSC 523258; 2,3,4,5-Tetrafluoro-1-bromobenzene; Perfluorobromobenzene (common, but not strictly accurate)
EINECS	214-048-8

Quality Control

Our 1-Bromo-2,3,4,5-tetrafluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and reproducible performance in critical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.85 g/mL
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.