Description

2-Bromo-6-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the toluene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and fluoro groups can enhance potency and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify molecular polarity and packing.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi), enabling the formation of new carbon-carbon bonds for complex molecule assembly.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the exploration of new synthetic pathways involving halogenated aromatics.
• Specialty Polymer Monomer: Can be utilized to synthesize functionalized polymers with specific properties like flame retardancy or altered refractive indices.

Basic Information

Product Name	2-Bromo-6-Fluorotoluene
CAS No.	1422-54-4
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	1-Bromo-2-fluoro-3-methylbenzene; 2-Fluoro-6-bromotoluene; 3-Methyl-2-fluorobromobenzene; o-Bromo-m-fluorotoluene; 2-Bromo-6-fluoro-1-methylbenzene; Toluene, 2-bromo-6-fluoro-; 2-Fluoro-6-methylbromobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorotoluene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.