Description

2-Amino-5-Fluoropyridine-3-Carboxamide is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a reactive amino group and a carboxamide function on a fluorinated pyridine ring, enabling the construction of complex pharmacophores. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocyclic compounds.

Basic Information

Product Name	2-Amino-5-Fluoropyridine-3-Carboxamide
CAS No.	958359-96-1
Molecular Formula	C6H6FN3O
Molecular Weight	155.13 g/mol
Synonyms	5-Fluoro-3-pyridinecarboxamide, 2-amino-; 2-Amino-5-fluoronicotinamide; 5-Fluoro-2-aminonicotinamide; 3-Carbamoyl-5-fluoro-2-aminopyridine; 2-Amino-5-fluoro-3-pyridinecarboxamide; 958359-96-1; 5-Fluoro-2-amino-3-pyridinecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoropyridine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with cGMP standards for advanced pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.