Description

2-Nitrobenzaldehyde Semicarbazone-13C, 15N2 is a stable isotope-labeled derivative of 2-nitrobenzaldehyde semicarbazone, specifically enriched with carbon-13 and nitrogen-15 isotopes. This compound is critically important for use as an internal standard in quantitative mass spectrometry, enabling highly accurate and precise analytical measurements. It is primarily needed by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Essential for quantitative bioanalysis in drug metabolism and pharmacokinetics (DMPK) studies to ensure data accuracy and compensate for matrix effects.
• Metabolite Tracing and Profiling: Used in stable isotope labeling experiments to track and identify drug metabolites in complex biological matrices.
• Pharmaceutical Impurity Analysis: Aids in the detection and quantification of process-related impurities and degradation products in active pharmaceutical ingredients (APIs).
• Environmental Fate Studies: Applied in research to monitor the degradation pathways and environmental persistence of nitroaromatic compounds.
• Forensic and Clinical Toxicology: Serves as a reference material for the confirmatory analysis of specific compounds in forensic and clinical samples.
• Chemical Synthesis Research: Used as a labeled building block or intermediate in the synthesis of more complex isotopically labeled molecules for research purposes.

Basic Information

Product Name	2-Nitrobenzaldehyde Semicarbazone-13C, 15N2
CAS No.	957509-32-9
Molecular Formula	C713C1H7N15N2O3
Molecular Weight	~197.11 g/mol (isotopic average)
Synonyms	2-Nitrobenzaldehyde-13C,15N2 semicarbazone; (2-Nitrobenzylidene)-13C,15N2 carbohydrazide; o-Nitrobenzaldehyde-13C,15N2 semicarbazone; 2-Nitrobenzaldehyde (13C,15N2) semicarbazone; Isotopically Labeled 2-Nitrobenzaldehyde Semicarbazone; [13C,15N2]-2-Nitrobenzaldehyde Semicarbazone; CAS 957509-32-9; 2-Nitrobenzaldehyde Semicarbazone (13C, 15N2)
EINECS	Contact for details

Quality Control

Our 2-Nitrobenzaldehyde Semicarbazone-13C, 15N2 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for demanding analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C and 15N), chemical purity by HPLC, and identity confirmation by NMR and MS. We adhere to cGMP principles for research chemicals, ensuring traceability, consistency, and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (Atom % 13C)	≥99%
Isotopic Enrichment (Atom % 15N)	≥98%
Chemical Purity (by 1H NMR)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.