Description

3-Carbamoyl-5-Chlorophenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its chlorophenyl and boronic acid functionalities.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where its structure allows for fine-tuning of material properties.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the creation of molecular probes for studying biological processes.
• Ligand and Catalyst Development: Utilized in the synthesis of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Carbamoyl-5-Chlorophenylboronic Acid
CAS No.	957120-53-5
Molecular Formula	C7H7BClNO3
Molecular Weight	199.40 g/mol
Synonyms	(3-Carbamoyl-5-chlorophenyl)boronic acid; 5-Chloro-3-carbamoylbenzeneboronic acid; 3-Aminocarbonyl-5-chlorobenzeneboronic acid; 3-Chloro-5-boronobenzamide; B-(3-Aminocarbonyl-5-chlorophenyl)boronic acid; 5-Chloronicotinamide boronic acid analog; CAS 957120-53-5
EINECS	Contact for details

Quality Control

Every batch of 3-Carbamoyl-5-Chlorophenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure compliance with exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.