Description

Boronic Acid, (3-Isothiocyanatophenyl)- (9Ci) is a specialized bifunctional organic compound that combines a boronic acid moiety with an isothiocyanate group. This unique structure makes it a versatile and critical building block for the synthesis of advanced materials and bioactive molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing targeted drug conjugates, sensors, and novel polymers.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing boronic acid-based protease inhibitors and other active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used to create fluorescent probes, affinity labels, and antibody-drug conjugates (ADCs) via its reactive isothiocyanate group.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boronic acid partner in palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Sensor & Diagnostic Agent Synthesis: Building block for developing selective chemosensors and diagnostic tools that leverage boronic acid-diol interactions.
• Polymer & Materials Science: Monomer for creating functionalized polymers with specific binding or sensing capabilities.
• Agrochemical Research: Intermediate in the development of novel herbicides and fungicides with targeted modes of action.

Basic Information

Product Name	Boronic Acid, (3-Isothiocyanatophenyl)- (9Ci)
CAS No.	133887-74-8
Molecular Formula	C7H6BNO2S
Molecular Weight	178.99 g/mol
Synonyms	(3-Isothiocyanatophenyl)boronic acid; 3-Isothiocyanatobenzeneboronic acid; 3-Isothiocyanatophenylboronic acid; B-(3-Isothiocyanatophenyl)boronic acid; 3-Boronophenyl isothiocyanate; m-Isothiocyanatophenylboronic acid; NSC 405124; Boronic acid, B-[3-(isothiocyanato)phenyl]-
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, (3-Isothiocyanatophenyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.