Description

3-(4-Fluorophenyl)Phenylboronic Acid is a high-purity organoboron compound, specifically a boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the specific fluorophenyl moiety can influence biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and in the development of new synthetic methodologies.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors that leverage boronic acid chemistry for detecting biological analytes.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories engaged in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	3-(4-Fluorophenyl)Phenylboronic Acid
CAS No.	159020-61-8
Molecular Formula	C12H10BFO2
Molecular Weight	216.02 g/mol
Synonyms	[3-(4-Fluorophenyl)phenyl]boronic acid; (3-(4-Fluorophenyl)phenyl)boronic acid; 3-(4-Fluorophenyl)benzeneboronic acid; 3-(p-Fluorophenyl)phenylboronic acid; 4-Fluoro-3'-biphenylboronic acid; B-[3-(4-Fluorophenyl)phenyl]boronic acid; 159020-61-8; 3-(4-Fluorophenyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay	≥95.0% (by titration)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.