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3-Chloro-4-Methylphenylboronic Acid CAS NO 175883-63-3


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CAS No.:175883-63-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Chloro-4-Methylphenylboronic Acid is a versatile organoboron compound widely used as a key synthetic intermediate in cross-coupling reactions. Its primary value lies in enabling the efficient construction of complex biaryl structures, which are crucial scaffolds in advanced material and pharmaceutical chemistry. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional polymers.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for creating carbon-carbon bonds to synthesize complex biaryl compounds.
  • Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.
  • Material Science & OLED Development: Employed in the synthesis of organic electronic materials, including ligands for catalysts and emissive layers.
  • Ligand Synthesis for Catalysis: Used to prepare specialized ligands for transition metal catalysts.
  • Chemical Research & Process Development: A valuable tool in academic and industrial laboratories for method development and scale-up studies.

Basic Information

Product Name 3-Chloro-4-Methylphenylboronic Acid
CAS No. 175883-63-3
Molecular Formula C7H8BClO2
Molecular Weight 170.40 g/mol
Synonyms (3-Chloro-4-methylphenyl)boronic acid; 3-Chloro-p-tolylboronic acid; (3-Chloro-4-methylphenyl)boronic acid; Boronic acid, B-(3-chloro-4-methylphenyl)-; 3-Chloro-4-methylbenzeneboronic acid; 175883-63-3; B-(3-Chloro-4-methylphenyl)boronic acid
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Quality Control

Our 3-Chloro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF Titration) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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