Description

6-Methoxybenzo[B]Thiophene-2-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	6-Methoxybenzo[B]Thiophene-2-Boronic Acid
CAS No.	182133-35-3
Molecular Formula	C9H9BO3S
Molecular Weight	208.04 g/mol
Synonyms	6-Methoxybenzo[b]thiophene-2-boronic acid; 6-Methoxy-1-benzothiophene-2-boronic acid; (6-Methoxybenzo[b]thiophen-2-yl)boronic acid; 2-Borono-6-methoxybenzo[b]thiophene; 6-Methoxy-2-benzothienylboronic acid; 182133-35-3; 6-Methoxybenzo[B]Thiophene-2-Boronic Acid Pinacol Ester (common derivative).
EINECS	Contact for details

Quality Control

Our 6-Methoxybenzo[B]Thiophene-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.