Description

6-Hydroxy-2-naphthaleneboronic acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), liquid crystal materials, and organic electronic components.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents containing a naphthalene core.
• Suzuki-Miyaura Cross-Coupling Reagent: Used extensively in palladium-catalyzed reactions to form carbon-carbon bonds, facilitating the creation of complex biaryl and heterobiaryl structures for advanced research and production.
• Agrochemical Synthesis: Employed in the development of new herbicides, fungicides, and insecticides where the naphthalene moiety imparts specific biological activity.
• Organic Electronic Materials: Serves as a building block for organic semiconductors, OLED (Organic Light-Emitting Diode) materials, and liquid crystals due to its rigid, planar structure and functional handles for further modification.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new catalytic methodologies and constructing molecular libraries for screening.
• Polymer Chemistry: Can be incorporated into polymer backbones or as a functional side group to create specialty polymers with tailored properties.
• Sensor Development: Utilized in the design of fluorescent probes and molecular sensors that leverage boronic acid's affinity for diols and other analytes.

Basic Information

Product Name	6-Hydroxy-2-naphthaleneboronic Acid
CAS No.	173194-95-1
Molecular Formula	C₁₀H₉BO₃
Molecular Weight	188.00 g/mol
Synonyms	6-Hydroxy-2-naphthylboronic acid; 2-Borono-6-hydroxynaphthalene; (6-Hydroxynaphthalen-2-yl)boronic acid; 6-Hydroxynaphthalene-2-boronic acid; 6-Hydroxy-2-naphthalene boronic acid; 6-Hydroxy-2-naphthaleneboronic acid pinacol ester (common derivative); 2-(6-Hydroxynaphthyl)boronic acid
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-2-naphthaleneboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.