Description

1-(Phenylsulfonyl)-1H-Indol-3-Ylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those containing indole or complex aryl-heteroaryl scaffolds for oncology, CNS, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biaryl linkages for enhanced activity and selectivity.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Catalyst & Ligand Development: Utilized in the preparation of specialized ligands for transition metal catalysis and organocatalysis.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	1-(Phenylsulfonyl)-1H-Indol-3-Ylboronic Acid
CAS No.	129271-98-3
Molecular Formula	C14H12BNO4S
Molecular Weight	301.13 g/mol
Synonyms	[3-(Boronyl)-1H-indol-1-yl]phenyl sulfone; 1-(Benzenesulfonyl)-1H-indole-3-boronic acid; 1H-Indole-3-boronic acid, 1-(phenylsulfonyl)-; 1-(Phenylsulfonyl)indole-3-boronic Acid; 3-Borono-1-(phenylsulfonyl)indole; N-(Phenylsulfonyl)indole-3-boronic acid; 1-(Phenylsulfonyl)indol-3-ylboronic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-1H-Indol-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.