Description

6-Methoxy-2-Naphthaleneboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid reagent for forming carbon-carbon bonds to create complex biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental tool for medicinal chemists and process chemists in lead optimization and route scouting.
• Fine Chemical Production: Integral to the custom synthesis of specialty chemicals and complex organic compounds.

Basic Information

Product Name	6-Methoxy-2-Naphthaleneboronic Acid
CAS No.	156641-98-4
Molecular Formula	C11H11BO3
Molecular Weight	202.02 g/mol
Synonyms	(6-Methoxynaphthalen-2-yl)boronic Acid; 2-(6-Methoxynaphthyl)boronic Acid; 6-Methoxy-2-naphthylboronic Acid; 6-Methoxynaphthalene-2-boronic Acid; B-(6-Methoxy-2-naphthalenyl)boronic Acid; 6-MONA; 2-Borono-6-methoxynaphthalene
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2-Naphthaleneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.