Description

2-Benzyloxyphenylboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is particularly critical for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially biphenyl derivatives and complex aromatic systems.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators requiring specific phenyl ether motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars, peroxides, and other analytes.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	2-Benzyloxyphenylboronic Acid
CAS No.	190661-29-1
Molecular Formula	C13H13BO3
Molecular Weight	228.05 g/mol
Synonyms	(2-Benzyloxyphenyl)boronic Acid; 2-(Benzyloxy)benzeneboronic Acid; B-(2-Benzyloxyphenyl)boronic Acid; 2-(Phenylmethoxy)phenylboronic Acid; [2-(Benzyloxy)phenyl]boronic Acid; 2-Benzyloxybenzeneboronic Acid; 2-Benzyloxy Phenyl Boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Benzyloxyphenylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.