Description

(+/-)-9-Deme-Dtbz CAS NO 956903-21-2 is a high-purity chemical intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of next-generation therapeutics. The material's defined stereochemistry and purity are essential for ensuring reproducible outcomes in complex synthetic sequences.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of compounds targeting specific neurotransmitter systems.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential drug substances.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Applied in studies investigating molecular interactions and binding assays.

Basic Information

Product Name	(+/-)-9-Deme-Dtbz
CAS No.	956903-21-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(±)-9-Deme-DTBZ; 9-Demethoxy-DTBZ; Dihydrotetrabenazine derivative; 9-O-Desmethyl DTBZ; Tetrabenazine analog; VMAT2 ligand intermediate; 2-Hydroxy-3-isobutyl-9-methoxy-10-methoxycarbonyl-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine derivative (racemic)
EINECS	Contact for details

Quality Control

Our (+/-)-9-Deme-Dtbz is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.