Description

4-(Oxazol-2-Yl)Benzenesulfonyl Chloride is a high-purity, specialized organic intermediate featuring a reactive sulfonyl chloride group linked to a substituted oxazole aromatic system. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development where it serves as a key building block. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for sulfonamide-based therapeutics targeting various enzymes and receptors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that leverage the sulfonyl chloride moiety for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, modifying, or inhibiting biological molecules in research applications.
• Ligand Synthesis: Useful for constructing complex ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific, multi-step synthetic projects requiring high-purity building blocks.

Basic Information

Product Name	4-(Oxazol-2-Yl)Benzenesulfonyl Chloride
CAS No.	956595-45-2
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	2-[4-(Chlorosulfonyl)phenyl]oxazole; 4-(2-Oxazolyl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 4-(2-oxazolyl)-; 4-(Oxazol-2-yl)phenylsulfonyl chloride; 1-(Oxazol-2-yl)-4-sulfonylchloridebenzene; 4-(1,3-Oxazol-2-yl)benzenesulfonyl chloride; 2-(4-Chlorosulfonylphenyl)oxazole
EINECS	Contact for details

Quality Control

Every batch of 4-(Oxazol-2-Yl)Benzenesulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical research and production processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques including HPLC, NMR, and MS. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.