Description

3,5-Dimethylbenzenesulfonyl Chloride is a versatile sulfonylating agent and a key organic synthesis intermediate. This compound is critical for introducing the 3,5-dimethylbenzenesulfonyl (mesitylenesulfonyl) group, a valuable moiety in medicinal chemistry and material science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drugs and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers and resins with specific functional groups.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and organic pigments.
• Chemical Research & Development: Employed as a sulfonylating agent in organic synthesis to protect amines or create sulfonate esters.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes and catalysts.

Basic Information

Product Name	3,5-Dimethylbenzenesulfonyl Chloride
CAS No.	2905-27-3
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	Mesitylenesulfonyl Chloride; 3,5-Dimethylphenylsulfonyl Chloride; 3,5-Dimethylbenzenesulphonyl Chloride; 3,5-Xylylsulfonyl Chloride; 1,3,5-Trimethylbenzenesulfonyl Chloride (common misnomer); Mesitylsulfonyl Chloride; 3,5-Dimethylbenzene-1-sulfonyl chloride
EINECS	220-824-6

Quality Control

Our 3,5-Dimethylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.