Description

1-Hexadecanesulfonyl Chloride is a high-purity, long-chain sulfonyl chloride derivative, a critical reagent in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation agent, enabling the introduction of the hydrophobic hexadecylsulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing surfactants, liquid crystal intermediates, and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing sulfonamide drugs and prodrugs with enhanced lipophilicity.
• Agrochemical Synthesis: Used in the production of specialized herbicides and fungicides requiring specific surfactant properties.
• Surfactant & Detergent Chemistry: Serves as a precursor for anionic surfactants with long alkyl chains for industrial and laboratory use.
• Polymer Modification: Employed to introduce sulfonyl groups into polymers, altering their solubility and surface characteristics.
• Liquid Crystal Materials: A valuable intermediate in the synthesis of components for display technologies.
• Chemical Research & Development: A fundamental reagent for exploring new sulfonylation reactions and creating novel chemical entities.
• Dye and Pigment Industry: Used in the synthesis of specialized sulfonated colorants.

Basic Information

Product Name	1-Hexadecanesulfonyl Chloride
CAS No.	38775-38-1
Molecular Formula	C₁₆H₃₃ClO₂S
Molecular Weight	324.95 g/mol
Synonyms	Hexadecane-1-sulfonyl chloride; Palmitylsulfonyl chloride; Cetyl sulfonyl chloride; n-Hexadecylsulfonyl chloride; 1-Sulfonylchloridohexadecane; NSC 403108
EINECS	Contact for details

Quality Control

Our 1-Hexadecanesulfonyl Chloride is produced under stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water and strong bases; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or flakes
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.