Description

2-Chloroethanesulfonyl Chloride is a versatile and highly reactive bifunctional organosulfur compound, serving as a critical building block in advanced chemical synthesis. Its dual functionality as both an alkylating agent and a sulfonyl chloride makes it indispensable for introducing the 2-chloroethanesulfonyl moiety into target molecules. This intermediate is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamides, sulfonate esters, and other complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing sulfonamide or sulfonate functional groups.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that require the chloroethanesulfonyl unit for bioactivity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, ion-exchange resins, and functionalized surfaces.
• Organic Synthesis Reagent: Employed in research laboratories for the preparation of sulfonyl chlorides, sulfonamides, and as an alkylating agent in multi-step synthetic routes.
• Dye & Pigment Manufacturing: Intermediate in the production of sulfonated dyes and colorants.
• Ligand & Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in coordination chemistry and catalysis.

Basic Information

Product Name	2-Chloroethanesulfonyl Chloride
CAS No.	1622-32-8
Molecular Formula	C2H4Cl2O2S
Molecular Weight	163.02 g/mol
Synonyms	2-Chloroethanesulfonyl chloride; 2-Chloroethane-1-sulfonyl chloride; 2-Chloroethylsulfonyl chloride; Chloroethanesulfonyl chloride; Ethanesulfonyl chloride, 2-chloro-; NSC 88171; β-Chloroethanesulfonyl chloride
EINECS	216-603-6

Quality Control

Our 2-Chloroethanesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards where required, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.55 g/cm³
Refractive Index (n20/D)	~1.488

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.