Description

3-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation and protecting group reagent, enabling the creation of complex molecules with precision. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) and other drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents that incorporate sulfonyl functional groups.
• Peptide Chemistry: Acts as a reagent for the introduction of sulfonyl protecting groups (e.g., Nosyl group) in peptide synthesis.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of sulfonated azo dyes and other colored compounds.
• Polymer Modification: Employed to introduce sulfonyl chloride functionalities into polymer chains for subsequent cross-linking or property enhancement.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new sulfonylation reactions and creating novel chemical libraries.

Basic Information

Product Name	3-Nitrobenzenesulfonyl Chloride
CAS No.	121-51-7
Molecular Formula	C6H4ClNO4S
Molecular Weight	221.62 g/mol
Synonyms	m-Nitrobenzenesulfonyl Chloride; 3-Nitrobenzene-1-sulfonyl Chloride; Benzenesulfonyl Chloride, 3-nitro-; NSC 403124; m-Nosyl Chloride; 3-Nitrobenzenesulphonyl Chloride; 1-Chlorosulfonyl-3-nitrobenzene
EINECS	204-476-3

Quality Control

Our 3-Nitrobenzenesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to relevant industry standards and can provide material suitable for research and commercial scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	63 - 67 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.