Description

1-(Difluoromethyl)-3,5-Dimethyl-1H-Pyrazole is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the difluoromethyl group, which serves as a key bioisostere, enabling the fine-tuning of physicochemical properties in target molecules. This compound is primarily needed by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl moiety enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, liquid crystals, and electronic materials with unique properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	1-(Difluoromethyl)-3,5-Dimethyl-1H-Pyrazole
CAS No.	956477-62-6
Molecular Formula	C6H8F2N2
Molecular Weight	146.14 g/mol
Synonyms	1-(Difluoromethyl)-3,5-dimethylpyrazole; 3,5-Dimethyl-1-(difluoromethyl)-1H-pyrazole; 1H-Pyrazole, 1-(difluoromethyl)-3,5-dimethyl-; Difluoromethyl-dimethylpyrazole; DFMP
EINECS	Contact for details

Quality Control

Our 1-(Difluoromethyl)-3,5-Dimethyl-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.