Description

3-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridine is a high-value, heterocyclic organic compound featuring a fused pyrazolopyridine core substituted with a trifluoromethyl group. This structure is critical for its role as a versatile and potent building block in modern pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and advanced material synthesis. The compound's unique electronic and steric properties make it an essential intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of small molecule drug candidates targeting various disease pathways, including kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Serves as a precursor for advanced organic electronic materials and ligands in catalytic systems.
• Chemical Biology: Employed as a probe or tag in biochemical assays due to its distinct structural and spectroscopic signature.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D pipelines.

Basic Information

Product Name	3-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	956010-87-0
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	3-(Trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-(trifluoromethyl)-; 3-Trifluoromethyl-1H-pyrazolo[3,4-b]pyridine; 3-(Trifluoromethyl)pyrazolo[3,4-b]pyridine; 3-CF3-1H-pyrazolo[3,4-b]pyridine; TFMPP (context-specific); 956010-87-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.