Description

4-[4-(Chlorosulphonyl)Phenyl]-1,3-Oxazole is a high-value, multi-functional chemical building block characterized by its reactive chlorosulphonyl and oxazole moieties. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), enabling the introduction of sulfonamide and heterocyclic functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-containing drug candidates, particularly for kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used to develop novel herbicides and fungicides by incorporating the oxazole-sulfonyl chloride scaffold.
• Material Science Research: Serves as a monomer or cross-linking agent for creating polymers with specific electronic or thermal properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions.
• Chemical Biology Probes: Utilized to tag or modify biomolecules for study due to its reactive sulfonyl chloride group.
• Custom Synthesis and Contract Manufacturing: A critical starting material for fine chemical and CDMO (Contract Development and Manufacturing Organization) projects.

Basic Information

Product Name	4-[4-(Chlorosulphonyl)Phenyl]-1,3-Oxazole
CAS No.	954368-94-6
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	4-(4-(Chlorosulfonyl)phenyl)oxazole; 4-(Oxazol-4-yl)benzenesulfonyl chloride; 1,3-Oxazole, 4-[4-(chlorosulfonyl)phenyl]-; 4-(4-Oxazolyl)benzenesulfonyl Chloride; Benzenesulfonyl chloride, 4-(4-oxazolyl)-; 4-(Oxazole-4-yl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-[4-(Chlorosulphonyl)Phenyl]-1,3-Oxazole is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.