Description

2-Chloro-3H-Benzoimidazole-5-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and chloro-substituted benzimidazole core. This compound matters for its critical role in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where it serves as a key building block for creating sulfonamide derivatives and heterocyclic compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzymes via sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require a benzimidazole-sulfonyl chloride scaffold.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing specialized dyes and organic pigments due to its fused aromatic structure.
• Material Science Research: Employed in the creation of advanced polymers and organic electronic materials where specific heterocyclic units are required.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and molecular tags for proteomics and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-3H-Benzoimidazole-5-Sulfonyl Chloride
CAS No.	954262-24-9
Molecular Formula	C7H4Cl2N2O2S
Molecular Weight	251.09 g/mol
Synonyms	2-Chloro-1H-benzimidazole-5-sulfonyl chloride; 2-Chloro-1H-benzo[d]imidazole-5-sulfonyl chloride; 1H-Benzimidazole-5-sulfonyl chloride, 2-chloro-; 2-Chloro-3H-benzimidazole-5-sulfonyl chloride; 2-Chloro-1H-benzimidazole-5-sulphonyl chloride; 954262-24-9; 2-Chloro-1H-benzoimidazole-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-3H-Benzoimidazole-5-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and agrochemical customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.