Description

Methyl 5-Fluoro-6-Methoxynicotinate CAS NO 953780-40-0 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile chemical handle for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Utilized as a probe or tag in the study of biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	Methyl 5-Fluoro-6-Methoxynicotinate
CAS No.	953780-40-0
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	Methyl 5-Fluoro-6-methoxypyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-fluoro-6-methoxy-, methyl ester; 5-Fluoro-6-methoxynicotinic acid methyl ester; 6-Methoxy-5-fluoronicotinic acid methyl ester; Methyl 5-fluoro-6-methoxynicotinate; 953780-40-0
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoro-6-Methoxynicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.