Description

5-(2,2,2-Trifluoroethoxy)Picolinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoroethoxy side chain and an aldehyde functional group, makes it indispensable for introducing specific fluorinated motifs into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for constructing complex ligands used in catalysis and material science.
• Fluorinated Material Research: Employed in academic and industrial R&D for creating novel fluorinated polymers and liquid crystals with specialized properties.
• Custom Synthesis Building Block: Essential for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis for clients.

Basic Information

Product Name	5-(2,2,2-Trifluoroethoxy)Picolinaldehyde
CAS No.	953780-30-8
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-Pyridinecarboxaldehyde, 5-(2,2,2-trifluoroethoxy)-; 5-(Trifluoroethoxy)-2-pyridinecarboxaldehyde; 5-(2,2,2-Trifluoroethoxy)pyridine-2-carbaldehyde; 5-(Trifluoroethoxy)picolinaldehyde; 2-Formyl-5-(2,2,2-trifluoroethoxy)pyridine; 5-(Trifluoroethoxy)-2-formylpyridine; 953780-30-8; 5-(2,2,2-Trifluoroethoxy)-2-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 5-(2,2,2-Trifluoroethoxy)Picolinaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and scale-up projects with material produced under current Good Manufacturing Practice (cGMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.