Description

6,7-Difluoro-1,2,3,4-Tetrahydroquinoline is a fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the difluoro motif can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as ligands for catalysis or components for organic electronics.
• Fluorine Chemistry Studies: An important substrate for methodological development in fluorination and selective functionalization chemistry.
• Ligand and Catalyst Development: The tetrahydroquinoline scaffold can be elaborated to create novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	6,7-Difluoro-1,2,3,4-Tetrahydroquinoline
CAS No.	953717-64-1
Molecular Formula	C9H9F2N
Molecular Weight	169.17 g/mol
Synonyms	6,7-Difluoro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6,7-difluoroquinoline; 6,7-Difluoro-3,4-dihydro-2H-quinoline; 6,7-Difluoro-1,2,3,4-tetrahydro-quinoline; 6,7-Difluorotetrahydroquinoline; 953717-64-1; 6,7-Difluoro THQ
EINECS	Contact for details

Quality Control

Our 6,7-Difluoro-1,2,3,4-Tetrahydroquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.