Description

5-(Chlorosulphonyl)-4-Methyl-1,3-Thiazole is a high-purity, reactive heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both a chlorosulfonyl group and a thiazole ring, makes it a versatile intermediate for constructing complex molecules with tailored properties. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty chemicals and dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of thiazole-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Specialty Chemical Building Block: Serves as a precursor for functional materials, liquid crystals, and advanced polymers requiring specific heterocyclic architectures.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex chromophores and specialty dyes due to the electron-rich thiazole core.
• Chemical Research & Development: An essential reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-(Chlorosulphonyl)-4-Methyl-1,3-Thiazole
CAS No.	953070-51-4
Molecular Formula	C4H4ClNO2S2
Molecular Weight	197.66 g/mol
Synonyms	4-Methyl-1,3-thiazole-5-sulfonyl chloride; 4-Methylthiazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-4-methylthiazole; 4-Methyl-5-thiazolesulfonyl chloride; 5-Chlorosulfonyl-4-methylthiazole; 4-Methylthiazole-5-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 5-(Chlorosulphonyl)-4-Methyl-1,3-Thiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.