Description

6-Oxo-1-[3-(Trifluoromethyl)Benzyl]-1,6-Dihydro-3-Pyridinecarbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its pyridinecarbaldehyde core and trifluoromethylbenzyl substituent. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, especially in areas targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with potential neurological or anti-inflammatory activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its reactive aldehyde and heterocyclic structure.
• Organic Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds, such as fused pyridines and functionalized piperidines.
• Agrochemical Development: Employed in the research phase for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Oxo-1-[3-(Trifluoromethyl)Benzyl]-1,6-Dihydro-3-Pyridinecarbaldehyde
CAS No.	952183-57-2
Molecular Formula	C14H10F3NO2
Molecular Weight	281.23 g/mol
Synonyms	1-(3-(Trifluoromethyl)benzyl)-6-oxo-1,6-dihydropyridine-3-carbaldehyde; 3-Formyl-1-[(3-trifluoromethyl)benzyl]-2(1H)-pyridinone; 1-[(3-Trifluoromethyl)phenyl]methyl]-6-oxo-1,6-dihydro-3-pyridinecarboxaldehyde; 6-Oxo-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carbaldehyde; 952183-57-2; 3-Pyridinecarboxaldehyde, 1,6-dihydro-1-[[3-(trifluoromethyl)phenyl]methyl]-6-oxo-
EINECS	Contact for details

Quality Control

Our 6-Oxo-1-[3-(Trifluoromethyl)Benzyl]-1,6-Dihydro-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.