Description

3-(4-Bromo-3-Fluorophenyl)Prop-1-Ene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, primarily serving as a key intermediate for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce specific bromo-fluoro-phenyl motifs into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated phenyl group.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and liquid crystals with tailored electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl and extended conjugated systems.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the creation of compound libraries for high-throughput screening.
• Fine Chemical Manufacturing: Integrated into multi-step synthetic routes for producing complex dyes, pigments, and optical brighteners.

Basic Information

Product Name	3-(4-Bromo-3-Fluorophenyl)Prop-1-Ene
CAS No.	951888-38-3
Molecular Formula	C9H8BrF
Molecular Weight	215.06 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-2-propene; 4-Bromo-3-fluoro-β-methylstyrene; 3-(4-Bromo-3-fluorophenyl)propene; 4-Bromo-3-fluorostyrene; (4-Bromo-3-fluorophenyl)ethylene; Allyl-4-bromo-3-fluorobenzene; 951888-38-3
EINECS	Contact for details

Quality Control

Our production of 3-(4-Bromo-3-Fluorophenyl)Prop-1-Ene adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.