Description

1,4-Benzodioxin-6-Carboxaldehyde, 5-Fluoro-2,3-Dihydro-8-Methoxy- is a high-purity, fluorinated benzodioxin derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile and functionalized scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific molecular complexity into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the benzodioxin core and fluorine atom can contribute to unique biological activity and environmental profile.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, organic semiconductors, or fluorinated polymers with tailored electronic or physical properties.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tool compounds for studying enzyme mechanisms or biological pathways due to its reactive aldehyde functionality.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific, complex organic molecules.

Basic Information

Product Name	1,4-Benzodioxin-6-Carboxaldehyde, 5-Fluoro-2,3-Dihydro-8-Methoxy-
CAS No.	951797-72-1
Molecular Formula	C10H9FO4
Molecular Weight	212.17 g/mol
Synonyms	5-Fluoro-8-methoxy-2,3-dihydro-1,4-benzodioxine-6-carbaldehyde; 6-Formyl-5-fluoro-8-methoxy-2,3-dihydro-1,4-benzodioxine; 5-Fluoro-8-methoxy-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxaldehyde; 5-Fluoro-8-methoxy-2,3-dihydro-1,4-benzodioxin-6-carbaldehyde; 951797-72-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 1,4-Benzodioxin-6-Carboxaldehyde, 5-Fluoro-2,3-Dihydro-8-Methoxy- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.