Description

2'-Bromo-5'-Fluoroacetophenone is a versatile and highly functionalized aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen substituents, which enable selective cross-coupling reactions and further derivatization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals due to its aromatic core and functional handles.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used extensively in research settings for method development and exploring new chemical reactions.

Basic Information

Product Name	2'-Bromo-5'-Fluoroacetophenone
CAS No.	1006-33-3
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	1-(2-Bromo-5-fluorophenyl)ethanone; 2-Bromo-5-fluoroacetophenone; 2'-Bromo-5'-fluoroacetophenone; 1-Acetyl-2-bromo-5-fluorobenzene; Ethanone, 1-(2-bromo-5-fluorophenyl)-; α-Bromo-α'-fluoroacetophenone; 2-Bromo-5-fluorophenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2'-Bromo-5'-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.