Description

1-(2,6-Difluorophenyl)Ethan-1-One is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Fine Chemical Production: Acts as a building block for other high-value fluorinated fine chemicals and specialty reagents.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Ethan-1-One
CAS No.	13670-99-0
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2',6'-Difluoroacetophenone; 2,6-Difluoroacetophenone; 1-Acetyl-2,6-difluorobenzene; Ethanone, 1-(2,6-difluorophenyl)-; NSC 403107; 2,6-Difluorophenyl methyl ketone; α,α'-Difluoroacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)Ethan-1-One is manufactured under strict quality management systems. We provide material that typically meets a purity standard of ≥98.0% (by HPLC), with specifications tailored to your process requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual unknown ≤ 0.5%, Total ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.