Description

3-Chloro-4-Fluorobenzaldehyde is a versatile halogenated aromatic aldehyde serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive formyl group adjacent to chloro and fluoro substituents, enabling precise molecular construction for high-value intermediates. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzaldehyde moiety.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic rings.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Serves as a starting material for synthesizing charge-transport or emissive materials in OLEDs.
• Dyestuff and Pigment Intermediate: Employed in the creation of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a suitable substrate for Palladium-catalyzed reactions like Suzuki or Sonogashira couplings.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating specialized compound libraries.

Basic Information

Product Name	3-Chloro-4-Fluorobenzaldehyde
CAS No.	34328-61-5
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	4-Fluoro-3-chlorobenzaldehyde; 3-Chloro-4-fluorobenzenecarboxaldehyde; 3-Chloro-4-fluorobenzene-1-carbaldehyde; 4-Fluoro-3-chlorobenzenecarboxaldehyde; 3-Chloro-4-fluorobenzaldehyde (primary IUPAC); 4-Fluoro-3-chlorobenzaldehyde; 3-Cl-4-F-BA (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorobenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.