Description

3-Fluorobenzaldehyde CAS NO 456-48-4 is a versatile aromatic aldehyde building block characterized by a fluorine substituent on the benzene ring. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, where the fluorine atom can significantly alter electronic properties and metabolic stability. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing advanced materials and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the fluorine atom enhances bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine moiety for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic electronic materials, contributing to the performance of displays and lighting.
• Fine Chemical & Dye Intermediate: Employed in the manufacture of specialty dyes, pigments, and flavor/fragrance compounds.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures in medicinal chemistry.
• Chemical Research & Development: A fundamental reagent for exploring new fluorination methodologies and creating novel fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	3-Fluorobenzaldehyde
CAS No.	456-48-4
Molecular Formula	C7H5FO
Molecular Weight	124.11 g/mol
Synonyms	m-Fluorobenzaldehyde; 3-Fluorobenzenecarboxaldehyde; Benzaldehyde, 3-fluoro-; m-Fluorobenzaldehyde; 3-Fluorobenzaldehyde; 3-Fluorophenyl aldehyde; m-Fluorobenzene aldehyde; 3-Fluorobenzene-1-carbaldehyde
EINECS	207-274-2

Quality Control

Our 3-Fluorobenzaldehyde is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.