Description

1-Fluoro-4-(Triethoxymethyl)Benzene is a specialized organofluorine building block featuring a reactive triethoxymethyl group. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, enabling the introduction of fluorinated aromatic systems. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting applications.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with altered solubility, thermal stability, or surface properties.
• Cross-coupling Reactions: The triethoxymethyl group can be transformed for use in palladium-catalyzed coupling reactions to build complex biaryl structures.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution and hydrolysis reactions to introduce aldehyde or other functional groups onto fluorinated benzene rings.

Basic Information

Product Name	1-Fluoro-4-(Triethoxymethyl)Benzene
CAS No.	10345-73-0
Molecular Formula	C13H19FO3
Molecular Weight	242.29 g/mol
Synonyms	p-Fluorobenzaldehyde Diethyl Acetal; 4-Fluorobenzaldehyde Diethyl Acetal; (4-Fluorophenyl)(triethoxy)methane; α,α,α-Triethoxy-4-fluorotoluene; Benzene, 1-fluoro-4-(triethoxymethyl)-; 4-Fluorobenzylidene Diethyl Acetal; Triethoxy(4-fluorophenyl)methane
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(Triethoxymethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.