Description

2-Fluoroacrolein is a highly reactive and versatile fluorinated building block essential for advanced organic synthesis. Its unique structure, featuring both an aldehyde and a fluorine-substituted alkene, makes it a critical intermediate for introducing fluorine atoms into complex molecular frameworks. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), potentially improving metabolic stability and bioavailability.
• Agrochemical Research: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers and advanced materials with specific surface properties.
• Organic Synthesis: A versatile reagent for cycloaddition reactions, such as Diels-Alder, and for constructing complex heterocycles.
• Fluorine Chemistry: Fundamental building block in academic and industrial research focused on developing new fluorination methodologies.
• Ligand and Catalyst Development: Precursor for synthesizing fluorinated ligands used in asymmetric catalysis and coordination chemistry.

Basic Information

Product Name	2-Fluoroacrolein
CAS No.	13989-27-0
Molecular Formula	C3H3FO
Molecular Weight	74.05 g/mol
Synonyms	2-Fluoroprop-2-enal; 2-Fluoroacrylaldehyde; Acrolein, 2-fluoro-; 2-Fluoro-2-propenal; 3-Fluoroacrolein; Fluoracrolein; 2-Fluoroacrylic aldehyde; Propenal, 2-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Fluoroacrolein is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended cold temperatures (e.g., 2-8°C or as specified). Keep away from heat, sparks, and open flame. Use only in a well-ventilated area or fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.