Description

1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Dione is a specialized organic compound featuring a trifluoromethylphenyl group attached to a 1,2-diketone (α-diketone) moiety. This structure makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex molecules, particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the α-diketone and fluorinated aryl groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs or photovoltaic components, due to its electron-accepting properties.
• Fluorinated Compound Library: An essential building block for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Research & Development: Used in academic and industrial labs for methodological studies and the exploration of new organic reactions involving α-diketones.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Dione
CAS No.	10557-15-0
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	3'-(Trifluoromethyl)phenylglyoxal; 1,2-Propanedione, 1-[3-(trifluoromethyl)phenyl]-; 3-(Trifluoromethyl)phenylglyoxal; α-Keto-3'-(trifluoromethyl)acetophenone; 2-Oxo-1-[3-(trifluoromethyl)phenyl]ethanone; m-Trifluoromethylphenylglyoxal; 3-Trifluoromethylphenylglyoxal
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Phenyl]Propane-1,2-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistent performance as a synthetic intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.