Description

n-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate-D3 is a deuterated derivative of a key sialic acid intermediate, offering a stable isotopic label for advanced research and analytical applications. This compound is critical for metabolic pathway tracing, pharmacokinetic studies, and the development of high-precision diagnostic assays where standard molecules lack the necessary specificity. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and manufacturers of reference standards in the life sciences sector.

Application

• Isotopic Internal Standard for the precise quantification of sialic acid derivatives in biological matrices using LC-MS/MS.
• Metabolic Tracer in glycobiology research to study sialic acid biosynthesis, turnover, and incorporation into glycoconjugates.
• Pharmaceutical Intermediate for the synthesis of deuterium-labeled drug candidates, enhancing metabolic stability studies.
• Reference Material for calibrating analytical instruments and validating methods in quality control laboratories.
• Biochemical Research tool for investigating enzyme mechanisms involving sialidases and sialyltransferases.
• Diagnostic Development as a critical component in the manufacture of assay kits for detecting sialic acid-related disorders.

Basic Information

Item	Detail
Product Name	n-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate-D3
CAS No.	950508-99-3
Molecular Formula	C21H26D3NO14
Molecular Weight	528.48 g/mol
Synonyms	Neu5Ac Methyl Ester Pentaacetate-D3; Methyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonic acid 2,4,7,8,9-pentaacetate-D3; Sialic Acid Methyl Ester Pentaacetate Deuterated; Methyl N-acetylneuraminate pentaacetate-D3; Peracetylated Neu5Ac Methyl Ester-D3; Deuterated Sialic Acid Derivative; 5-N-Acetyl-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid methyl ester-D3
EINECS	Contact for details

Quality Control

Every batch of n-Acetylneuraminic Acid Methyl Ester 2,4,7,8,9-Pentaacetate-D3 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet stringent specifications. Our quality management system supports the production of materials suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, deuterium enrichment, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.