Description

5,8-Difluoroquinolin-2(1H)-One is a high-value fluorinated quinolinone derivative, serving as a critical building block in advanced organic synthesis. Its unique difluoro-substituted quinolinone core is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily required by pharmaceutical R&D and agrochemical innovators for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, including organic electronic materials and fluorescent dyes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	5,8-Difluoroquinolin-2(1H)-One
CAS No.	949900-36-1
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	5,8-Difluoro-1,2-dihydro-2-oxoquinoline; 5,8-Difluoro-2-hydroxyquinoline; 5,8-Difluoro-2(1H)-quinolinone; 2-Hydroxy-5,8-difluoroquinoline; 5,8-Difluoroquinolin-2-ol; 1H-Quinolin-2-one, 5,8-difluoro-; 949900-36-1
EINECS	Contact for details

Quality Control

Our 5,8-Difluoroquinolin-2(1H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.