Description

15-Keto-17-Phenyl Trinor Prostaglandin F2α CAS NO 949564-89-0 is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise biological activity and structural specificity, enabling the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing treatments for ophthalmic conditions, cardiovascular regulation, and other prostaglandin-mediated pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based drugs, particularly for glaucoma and ocular hypertension treatments.
• Biochemical Research: Used as a reference standard and active probe in studies of prostaglandin receptors (FP receptors) and their signaling pathways.
• Drug Discovery & Development: Serves as a key precursor for creating analogs with modified potency, selectivity, and metabolic stability for preclinical evaluation.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of high-value, complex active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a certified reference material for quality control and method validation in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	15-Keto-17-Phenyl Trinor Prostaglandin F2α
CAS No.	949564-89-0
Molecular Formula	C₂₄H₃₄O₅
Molecular Weight	402.53 g/mol
Synonyms	15-Keto-17-phenyl-18,19,20-trinorprostaglandin F2α; 17-Phenyl-18,19,20-trinor-PGF2α-15-one; PF-04475270; 15-Oxo-17-phenyl-13,14-dihydro-18,19,20-trinorprostaglandin F2α; 15-Keto-17-phenyl-trinor-PGF2α; Travoprost Impurity; Prostaglandin F2α analog; FP receptor agonist intermediate
EINECS	Contact for details

Quality Control

Our 15-Keto-17-Phenyl Trinor Prostaglandin F2α is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with client-specific or general research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and degradation. For long-term storage, keep the material desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.