Description

7A-Homo-2-Norprostacyclin is a synthetic prostacyclin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural role in the synthesis of novel prostaglandin-based therapeutics targeting cardiovascular and pulmonary conditions. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostacyclin receptor agonists and prostaglandin analogs.
• Cardiovascular Research: Used in preclinical studies to investigate mechanisms related to vasodilation, platelet aggregation inhibition, and pulmonary arterial hypertension.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to develop new chemical entities with improved stability and efficacy.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Biochemical Research: Utilized in studies exploring prostaglandin signaling pathways and receptor interactions.

Basic Information

Product Name	7A-Homo-2-Norprostacyclin
CAS No.	100307-96-8
Molecular Formula	C₂₂H₃₄O₅
Molecular Weight	378.50 g/mol
Synonyms	7a-Homo-2-norprostacyclin; 7a-Homo-2-nor-PGI2; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-(3-oxooctyl)-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid; 7a-Homo-2-nor-prostacyclin; 7a-Homo-2-nor-PGI₂; 7a-Homo-2-nor-epoprostenol analog; Prostacyclin analog intermediate
EINECS	Contact for details

Quality Control

Our 7A-Homo-2-Norprostacyclin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is light-sensitive and easily oxidized. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.