Description

15(R)-Prostaglandin E1 is a stereoisomer of the naturally occurring lipid mediator Prostaglandin E1 (Alprostadil). This compound is a high-value pharmaceutical intermediate and research chemical of significant interest due to its distinct biological activity profile compared to its S-isomer. It is primarily utilized in advanced biomedical research and the development of novel therapeutic agents targeting inflammation, vascular tone, and cellular signaling pathways. Key industries requiring this precise stereochemistry include pharmaceutical R&D, biotechnology, and academic research institutions focused on prostaglandin biology.

Application

• Pharmaceutical Intermediate: Critical starting material or building block in the synthesis of specialized prostaglandin-based drugs.
• Biomedical Research: Used as a reference standard and active agent in studies investigating vascular biology, inflammation, and smooth muscle contraction.
• Cell Signaling Studies: Employed to study the role of specific prostaglandin receptor (EP receptor) subtypes in cellular processes.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore for designing new molecules with targeted therapeutic effects.
• Analytical Standard: Used in HPLC, LC-MS, and other analytical methods for method development, validation, and quality control of related substances.

Basic Information

Product Name	15(R)-Prostaglandin E1
CAS No.	19313-28-1
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	15(R)-PGE1; (15R)-Prostaglandin E1; 15R-PGE1; Alprostadil (15R-isomer); (5Z,11α,13E,15R)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 15-epi-Prostaglandin E1; PGA1, 15R-; Prostaglandin E1, 15R-
EINECS	Contact for details

Quality Control

Our 15(R)-Prostaglandin E1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.