Description

(5E,7Z,14Z)-10-Chloro-12-Hydroxy-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of bioactive molecules targeting specific inflammatory and physiological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in studies of eicosanoid signaling pathways and receptor interactions.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Development: Employed in scaling up synthetic routes for the production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in lipid biochemistry and inflammation.

Basic Information

Product Name	(5E,7Z,14Z)-10-Chloro-12-Hydroxy-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester
CAS No.	100295-79-2
Molecular Formula	C21H27ClO5
Molecular Weight	394.89 g/mol
Synonyms	10-Chloro-12-hydroxy-9-oxoprosta-5,7,10,14-tetraenoic acid methyl ester; Methyl 10-chloro-12-hydroxy-9-oxoprosta-5,7,10,14-tetraenoate; 10-Chloro-12-hydroxy-9-oxo-PG methyl ester; Prostaglandin A2 methyl ester derivative; PGA2 methyl ester analog; Chlorinated prostaglandin intermediate; CAS 100295-79-2
EINECS	Contact for details

Quality Control

Our (5E,7Z,14Z)-10-Chloro-12-Hydroxy-9-Oxoprosta-5,7,10,14-Tetren-1-Oic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. The container should be kept in a dry, well-ventilated area. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.