Description

15-Ketoprostaglandin I2 is a stable, biologically active metabolite of prostacyclin (PGI2) with significant research and pharmaceutical interest. This compound serves as a crucial reference standard and a key intermediate in the synthesis of novel prostaglandin analogs. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for cardiovascular research, drug discovery, and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of prostaglandin analogs in quality control (QC) and research and development (R&D) laboratories.
• Biochemical Research: A vital tool for studying the metabolism, signaling pathways, and biological effects of prostacyclin and its derivatives in cardiovascular and inflammatory models.
• Drug Discovery Intermediate: Serves as a key synthetic building block for the development of new therapeutic agents targeting platelet aggregation, vasodilation, and pulmonary hypertension.
• Analytical Method Development: Employed to validate high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and other analytical techniques for prostaglandin analysis.

Basic Information

Item	Detail
Product Name	15-Ketoprostaglandin I2
CAS No.	100311-07-7
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	15-Keto-prostacyclin I2; 15-Keto-PGI2; 9-Deoxy-9α,15α-dihydroxy-11-oxoprosta-5,13-dien-1-oic acid; 15-Ketoprostacyclin; 15-Oxoprostacyclin; 15-Keto PGI2; U-51605; 15-Keto prostaglandin I2
EINECS	Contact for details

Quality Control

Our 15-Ketoprostaglandin I2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.