Description

(+)-Cloprostenol Isopropyl Ester CAS NO 157283-66-4 is a high-purity, synthetic prostaglandin analog specifically formulated as the isopropyl ester derivative of cloprostenol. This compound is critically important for its potent luteolytic and smooth muscle-contracting properties, making it a key active pharmaceutical ingredient (API) and research tool. It is primarily needed by pharmaceutical manufacturers, veterinary medicine producers, and advanced life science research institutions developing treatments for reproductive health and other physiological conditions.

Application

• Veterinary Pharmaceutical API: Core active ingredient in injectable formulations for estrus synchronization and the treatment of reproductive disorders in livestock, such as cattle and swine.
• Human Pharmaceutical Research: Investigational compound in preclinical and clinical studies targeting conditions like glaucoma, pulmonary hypertension, and ulcer healing.
• Biochemical Research: A critical tool for studying prostaglandin F2α receptor (FP receptor) signaling pathways and their role in various physiological processes.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation of related pharmaceutical products.
• Reproductive Health Products: Intermediate or API in the development of fertility control and management solutions.

Basic Information

Product Name	(+)-Cloprostenol Isopropyl Ester
CAS No.	157283-66-4
Molecular Formula	C22H29ClO6
Molecular Weight	424.92 g/mol
Synonyms	(+)-Cloprostenol Isopropyl Ester; Cloprostenol Isopropyl Ester; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoic Acid Isopropyl Ester; PGF2α analog; EstroPLAN; Estrumate; ICI 80996 (Isopropyl Ester)
EINECS	Contact for details

Quality Control

Our (+)-Cloprostenol Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) are provided with each shipment, detailing all test results against release criteria.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. The product is light-sensitive; keep the original container sealed in a cool, dry place away from moisture and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.