Description

Prostaglandin A1 (PGA1) is a naturally occurring cyclopentenone prostaglandin, a key member of the eicosanoid family of bioactive lipid mediators. This compound is of significant interest in biochemical and pharmaceutical research due to its unique biological activities, which include anti-inflammatory, antiviral, and potential anti-proliferative effects. It serves as a critical reference standard and a valuable synthetic intermediate for researchers and manufacturers in the life sciences, pharmaceutical development, and advanced organic synthesis sectors.

Application

• Biochemical Research: Used as a high-purity reference standard for analytical method development, calibration, and quality control in prostaglandin analysis.
• Pharmaceutical R&D: Investigated as a lead compound or synthetic precursor for developing novel therapeutic agents targeting inflammation, viral infections, and cellular proliferation.
• Cell Signaling Studies: Employed in vitro and in vivo to study the role of cyclopentenone prostaglandins in cellular pathways, gene expression, and apoptosis.
• Organic Synthesis: Serves as a sophisticated chiral building block for the total synthesis of complex natural products and prostaglandin analogs.
• Academic Research: A fundamental tool in university and institutional labs for exploring lipid mediator biology and eicosanoid chemistry.

Basic Information

Product Name	Prostaglandin A1
CAS No.	14152-28-4
Molecular Formula	C₂₀H₃₀O₄
Molecular Weight	334.45 g/mol
Synonyms	PGA1; (5Z,13E)-(15S)-9-Oxo-11α,15-dihydroxyprosta-5,13-dien-1-oic acid; 15(S)-PGA1; 9-Oxo-11α,15-dihydroxyprosta-5,13-dien-1-oic acid; Prostaglandin A1; (15S)-PGA1; 11α,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
EINECS	238-025-6

Quality Control

Our Prostaglandin A1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.