Description

(25S)-δ7-Dafachronic Acid CAS NO 949004-12-0 is a high-purity, synthetic steroid hormone analog that serves as a potent ligand for the DAF-12 nuclear receptor. This compound is of significant value in biochemical and pharmaceutical research for its role in modulating developmental and metabolic pathways. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and biotechnology sectors for studying aging, metabolism, and gene regulation.

Application

• Research Chemical: A key tool compound for studying the DAF-12 signaling pathway in model organisms like C. elegans.
• Aging & Longevity Research: Used in mechanistic studies to investigate hormonal regulation of lifespan and developmental timing.
• Metabolic Pathway Analysis: Employed in research focused on steroid hormone signaling and its impact on metabolism.
• Pharmaceutical R&D: Serves as a reference standard and starting material in the discovery of novel therapeutics targeting nuclear hormone receptors.
• Cell Signaling Studies: Applied in in vitro assays to activate DAF-12 and study downstream gene expression effects.
• Biochemical Reagent: Used in receptor binding assays and as a critical component in specialized cell culture media for developmental studies.

Basic Information

Product Name	(25S)-δ7-Dafachronic Acid
CAS No.	949004-12-0
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	(25S)-δ7-Dafachronic Acid; δ7-Dafachronic Acid (25S-isomer); 3-Oxo-25S-cholesta-7,24-dien-26-oic Acid; Dafachronic Acid δ7-isomer; DAF-12 Ligand; 25S-δ7-DA; 949004-12-0; (25S)-3-Oxocholesta-7,24-dien-26-oic Acid
EINECS	Contact for details

Quality Control

Our (25S)-δ7-Dafachronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and custom synthesis to meet specific purity requirements (e.g., >95%, >98%) is available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.