Description

5-Bromo-1,2-Difluoro-3-(2-Methoxy-Ethoxy)-Benzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique halogen and ether substituents, which make it a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated difluorobenzene core.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal or optical properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination due to the bromine substituent.
• Chemical Research: Employed in academic and industrial labs for methodological studies and the development of new synthetic pathways.

Basic Information

Product Name	5-Bromo-1,2-Difluoro-3-(2-Methoxy-Ethoxy)-Benzene
CAS No.	947534-38-5
Molecular Formula	C9H9BrF2O2
Molecular Weight	267.07 g/mol
Synonyms	1-Bromo-2,3-difluoro-4-(2-methoxyethoxy)benzene; 2,3-Difluoro-5-bromo-1-(2-methoxyethoxy)benzene; 3-Bromo-4,5-difluorophenyl 2-methoxyethyl ether; 947534-38-5; 5-Bromo-1,2-difluoro-3-(2-methoxyethoxy)benzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2-Difluoro-3-(2-Methoxy-Ethoxy)-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.